Friday, February 8, 2008

Antioxidents And Free Radicals

Active MansAntioxidants
The process of oxidation in the human body damages cell membranes and other structures including cellular proteins, lipids and DNA. When oxygen is metabolised, it creates ‘free radicals’ which steal electrons from other molecules, causing damage.

The body can cope with some free radicals and needs them to function effectively. However, an overload of free radicals has been linked to certain diseases, including heart disease, liver disease and some cancers. Oxidation can be accelerated by stress, cigarette smoking, alcohol, sunlight, pollution and other factors.

Antioxidents and free radicals
Antioxidants are found in certain foods that neutralise free radicals. These include the nutrient antioxidants, vitamins A, C and E, and the minerals copper, zinc and selenium. Other dietary food compounds, such as the phytochemicals in plants and zoochemicals from animal products, are believed to have greater antioxidant effects than either vitamins or minerals. These are called the non-nutrient antioxidants and include phytochemicals, such as lycopenes in tomatoes, and anthocyanins found in cranberries.

Vitamin supplements
Some studies suggest that antioxidants are less effective when isolated from food and presented in tablet form. For instance, vitamin A (beta-carotene) has been associated with a reduced risk of certain cancers but an increase in others, such as lung cancer in smokers, if vitamin A is purified from foodstuffs.

A study examining the effects of vitamin E found that it didn’t offer the same benefits when taken as a supplement. Also, antioxidant minerals or vitamins can act as pro-oxidants or damaging ‘oxidants’ if they are consumed at levels significantly above the recommended amounts for dietary intake.

A well-balanced diet, which includes consuming antioxidants from whole foods, is best. If you insist on taking a supplement, seek supplements that contain all nutrients at the recommended levels.

Antioxidant

Active MansAn antioxidant is a chemical that reduces the rate of particular oxidation reactions in a specific context, where oxidation reactions are chemical reactions that involve the transfer of electrons from a substance to an oxidizing agent, this generally results in different chemicals to the original ones. Antioxidants are particularly important in the context of organic chemistry and biology.

All living organisms maintain a reducing environment inside their cells, all cells contain complex systems of antioxidants to prevent chemical damage to the cells' components by oxidation.

These antioxidants include glutathione and ascorbic acid and are substrates for enzymes such as peroxidases and oxidoreductases. Antioxidants are widely used as ingredients in dietary supplements used for health purposes such as preventing cancer and heart disease.

Studies have suggested antioxidant supplements has benefits for health, but several large clinical trials did not demonstrate a definite benefit for the formulations tested, and excess supplementation may even be harmful. Dietary supplementation has few specific antioxidants compared to a broad diet rich in phytonutrients, which will yield thousands of different polyphenol antioxidants available for metabolism..